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    SEC Form S-8 POS filed by Clearside Biomedical Inc.

    12/15/25 4:04:48 PM ET
    $CLSD
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $CLSD alert in real time by email
    S-8 POS 1 d89951ds8pos.htm S-8 POS S-8 POS

    As filed with the Securities and Exchange Commission on December 15, 2025

    Registration No. 333-212014

    Registration No. 333-216750

    Registration No. 333-224826

    Registration No. 333-231383

    Registration No. 333-238133

    Registration No. 333-256212

    Registration No. 333-264885

    Registration No. 333-271877

    Registration No. 333-279334

    Registration No. 333-287321

     

     
     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    WASHINGTON, D.C. 20549

     

     

    Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-212014

    Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-216750

    Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-224826

    Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-231383

    Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-238133

    Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-256212

    Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-264885

    Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-271877

    Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-279334

    Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-287321

    UNDER

    THE SECURITIES ACT OF 1933

     

     

    Clearside Biomedical, Inc.

    (Exact name of Registrant as Specified in Its Charter)

     

     

     

    Delaware   45-2437375

    (State or other jurisdiction of

    Incorporation or organization)

     

    (I.R.S. Employer

    Identification No.)

    900 North Point Parkway, Suite 200

    Alpharetta, Georgia 30005

    (Address of Principal Executive Offices)

     

     

    2011 Stock Incentive Plan, as amended

    Stock Option Awards

    2016 Equity Incentive Plan

    2016 Employee Stock Purchase Plan

    (Full titles of the plans)

     

     

    George Lasezkay, Pharm.D., J.D.

    President and Chief Executive Officer

    Clearside Biomedical, Inc.

    900 North Point Parkway, Suite 200

    Alpharetta, Georgia 30005

    (678) 270-3631

    (Name, address and telephone number, including area code, of agent for service)

     

     

    Copies to:

    Mark Ballantyne

    Paul Alexander

    Cooley LLP

    11951 Freedom Drive

    Reston, VA 20190

    (703) 456-8000

     

     

    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

     

    Large accelerated filer   ☐    Accelerated filer   ☐
    Non-accelerated filer   ☒    Smaller reporting company   ☒
         Emerging growth company   ☐

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

     

     
     


    DEREGISTRATION OF SECURITIES

    Clearside Biomedical, Inc., a Delaware corporation (the “Company”), is filing these post-effective amendments (these “Post-Effective Amendments”) to the following Registration Statements on Form S-8 (collectively, the “Registration Statements”), which have been previously filed with the U.S. Securities and Exchange Commission (the “SEC”), to deregister any and all shares of the Company’s common stock, par value $0.001 per share (“Common Stock”), registered but unsold or otherwise unissued under each such Registration Statement as of the date hereof:

     

      •  

    Registration File No. 333-212014, filed with the SEC on June 14, 2016, registering 1,261,637 shares of Common Stock reserved for issuance upon the exercise of outstanding stock options granted under the Company’s 2011 Stock Incentive Plan, as amended (the “2011 Plan”); 17,236 shares of common stock reserved for issuance upon the exercise of an outstanding option granted to Richard Croarkin outside of any plan; 1,818,182 shares of common stock reserved for the grant of future stock awards under the Company’s 2016 Equity Incentive Plan (the “2016 Plan”); and 181,818 shares of Common Stock issuable under the Company’s 2016 Employee Stock Purchase Plan (the “2016 ESPP”);

     

      •  

    Registration File No. 333-216750, filed with the SEC on March 16, 2017, registering 982,921 shares of Common Stock issuable under the 2016 Plan and 245,730 shares of Common Stock issuable under the 2016 ESPP;

     

      •  

    Registration File No. 333-224826, filed with the SEC on May 10, 2018, registering 1,014,186 shares of Common Stock issuable under the 2016 Plan and 253,546 shares of Common Stock issuable under the 2016 ESPP;

     

      •  

    Registration File No. 333-231383, filed with the SEC on May 10, 2019, registering 1,284,769 shares of Common Stock issuable under the 2016 Plan;

     

      •  

    Registration File No. 333-238133, filed with the SEC on May 8, 2020, registering 1,776,534 shares of Common Stock issuable under the 2016 Plan;

     

      •  

    Registration File No. 333-256212, filed with the SEC on May 17, 2021, registering 2,074,437 shares of Common Stock issuable under the 2016 Plan;

     

      •  

    Registration File No. 333-264885, filed with the SEC on May 12, 2022, registering 2,388,917 shares of Common Stock issuable under the 2016 Plan;

     

      •  

    Registration File No. 333-271877, filed with the SEC on May 12, 2023, registering 2,425,593 shares of Common Stock issuable under the 2016 Plan;

     

      •  

    Registration File No. 333-279334, filed with the SEC on May 10, 2024, registering 2,514,033 shares of Common Stock issuable under the 2016 Plan; and

     

      •  

    Registration File No. 333-287321, filed with the SEC on May 15, 2025, registering 3,063,135 shares of Common Stock issuable under the 2016 Plan.

    By filing these Post-Effective Amendments, the Company has terminated any and all offerings of its securities pursuant to the Registration Statements. Accordingly, the Company hereby terminates the effectiveness of each Registration Statement and, in accordance with an undertaking made by the Company in Part II of each Registration Statement to remove from registration, by means of post-effective amendment, removes from registration any and all securities of the Company registered for issuance but remain unsold or otherwise unissued under the Registration Statements as of the date hereof.


    SIGNATURES

    Pursuant to the requirements of the Securities Act of 1933, as amended, the Company certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused these Post-Effective Amendments to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Alpharetta, State of Georgia, on this 15th day of December, 2025.

     

    CLEARSIDE BIOMEDICAL , INC.
    By:   /s/ Charles A. Deignan
     

    Charles A. Deignan

    Chief Financial Officer

    No other person is required to sign these Post-Effective Amendments in reliance upon Rule 478 under the Securities Act of 1933, as amended.

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